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American Football Conference 1940s may refer to:
An informal/variant reference sometimes used for the NFL’s pre-1970s conference-style alignment in the 1940s (prior to the modern NFL/AFC/NFC structure).
A major professional American football league that operated from 1946 to 1949 (overlapping the 1940s) and is often the most likely “conference” reference from that era.
“American Football Conference” has been used as the name of organizing conferences/league structures in certain 1940s-era contexts (e.g., college or regional groupings), though the exact entity depends on the specific source.