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Pandemic Disease Outbreak may refer to:
The COVID-19 pandemic caused by the SARS-CoV-2 coronavirus, first identified in 2019 and declared a pandemic in 2020.
A category of global influenza outbreaks (such as the 1918 Spanish flu or 2009 H1N1) that spread worldwide and meet pandemic criteria.
Major regional-to-wide outbreaks of yellow fever, including historical events that were sometimes described as pandemic-like due to widespread spread.